Mapping human tissues with highly multiplexed RNA in situ hybridization.
Kalhor K, Chen CJ, Lee HS, Cai M, Nafisi M, Que R, Palmer CR, Yuan Y, Zhang Y, Li X, Song J, Knoten A, Lake BB, Gaut JP, Keene CD, Lein E, Kharchenko PV, Chun J, Jain S, Fan JB, Zhang K.
Kalhor K, et al.
Nat Commun. 2024 Mar 20;15(1):2511. doi: 10.1038/s41467-024-46437-y.
Nat Commun. 2024.
PMID: 38509069
Free PMC article.
Our enzyme-free isothermal decoding procedure allows us to image 121 genes in large sections from the human neocortex in <10 h. We successfully recapitulated the cytoarchitecture of 20 neuronal and non-neuronal subclasses. ...
Our enzyme-free isothermal decoding procedure allows us to image 121 genes in large sections from the human neocortex in <10 h. We …